Pepto Bismol Ultra Strength-Original Flavor. When you have a sour stomach, Pepto's improved formula coats your stomach and provides fast relief from nausea, heartburn, indigestion, upset stomach, and diarrhea. Pepto Bismol ULTRA STRENGTH has got you covered. 5 SYMPTOM Digestive Relief: Nausea, Heartburn, Indigestion, Upset Stomach, Diarrhea (Packaging may vary) The #1 Pharmacist Recommended Brand for Upset Stomachs (Based on Pharmacy Times 2018 Survey-upset stomach remedies category) Pepto's formula now has improved coating to calm and soothe your stomach Bismuth Subsalicylate Whether you're looking for an upset stomach medicine or nausea help, wondering what to do for indigestion or heartburn relief, or trying to find what's good for diarrhea, Pepto provides fast relief